奥美拉唑镁肠溶片与西咪替丁联合治疗反流性食管炎临床观察

Clinical observation of omeprazole magnesium enteric-coated tablets combined with cimetidine in the treatment of reflux esophagitis

目的:观察、分析奥美拉唑镁肠溶片与西咪替丁联合治疗反流性食管炎的效果。方法:收治反流性食管炎患者62例,随机平分两组。对比组单纯使用奥美拉唑镁肠溶片,联合组采用奥美拉唑镁肠溶片与西咪替丁联合治疗。对比不同方案治疗后两组治疗效果和复发情况。结果:经过治疗后,联合组的治疗效果要优于对比组,差异有统计学意义(P<0.05)。联合组临床治疗效果高于对比组,差异有统计学意义(P<0.05)。结论:使用奥美拉唑镁肠溶片与西咪替丁联合治疗反流性食管炎效果显著,大大改善了病情。

Objective:To investigate the effect of omeprazole magnesium enteric-coated tablets combined with cimetidine in the treatment of reflux esophagitis.Methods:62patients with reflux esophagitis were selected.They were randomly divided into the two groups on average.The contrast group only used omeprazole magnesium enteric-coated tablets,and the combined group was treated with omeprazole magnesium enteric-coated tablets combined with cimetidine.The treatment effect and recurrence of the patients in the contrast group and the combined group were compared after different treatment.Results:After treatment,the treatment effect of the combined group was better than that of the contrast group,and the difference was statistically significant(P<0.05).The clinical effect of the combined group was higher than that of the contrast group,and the difference was statistically significant(P<0.05).Conclusion:The use of omeprazole magnesium enteric-coated tablets combined with cimetidine in the treatment of reflux esophagitis has significant effect,which can greatly improve the condition.