中枢神经系统原发性黑色素肿瘤的临床特征及病理特征分析

Analysis of clinical and pathological characteristics of primary melanocytomas in central nervous system

目的探讨中枢神经系统原发性黑色素肿瘤的临床表现、病理特征及手术效果。方法回顾性分析2003年3月至2017年2月手术治疗的3例中枢神经系统原发性黑色素性肿瘤的临床资料,1例位于颞叶,1例位于小脑,1例位于右侧桥小脑角区。结果 2例全切,1例次全切。术后随访1~3个月,3例一般情况良好。结论中枢神经系统原发性黑色素肿瘤确诊依赖病理检查,临床分型对判断预后有重要意义。

Objective To investigate the clinical and pathological characteristics,diagnosis and treatment of primary melanocytomas in the central nervous system(CNS).Methods The clinical data of3patients with CNS primary melanocytomas,who underwent microsurgery from March,2003to February,2017,were analyzed retrospectively.Of3patients with CNS primary melanocytomas,1had tumor in the temporal lobe,1in the cerebellum,and1in the right cerebellopontine angle.Results The total resection of melanocytomas was achieved in3patients.One patient survived and the others lost following-up3months after the operation.Conclusions The CNS primary melanocytoma is a rare tumor.Its diagnosis depends on immune phenotype and clinical classification is important for the prognosis in the patient with CNS primary melanocytoma.