血清降钙素原、白细胞介素、肿瘤坏死因子和全血超敏C-反应蛋白用于小儿细菌性肺炎检测的效果分析

Effect of PCT, IL, TNF-α and hs-CRP in the detection of bacterial pneumonia in children

目的探讨在小儿细菌性肺炎中检测血清降钙素原(procalcitonin,PCT)、白细胞介素(IL-6、IL-8)与肿瘤坏死因子(tumor necrosis factor-α,TNF-α)和全血超敏C-反应蛋白(hypersensitive C-reactive protein,hs-CRP)的临床效果。方法选取2015年6月-2016年6月我院检验科收治的细菌性肺炎患儿50例为观察组,选择同期于我院体检的健康儿童50例为对照组,检测并比较两组小儿的PCT、IL-6、IL-8、TNF-α与hs-CRP水平。结果观察组小儿的各项指标水平均明显高于对照组,差异均有统计学意义(P<0.05)。结论血清PCT、IL-6、IL-8、TNF-α与hs-CRP水平用于检测小儿细菌性肺炎临床效果明显,值得临床推广。

Objective To investigate the clinical effect of detection of procalcitonin(PCT),interleukin(IL),tumor necrosis factor-α(TNF-α)and hypersensitive C-reactive protein(hs-CRP)in children with bacterialpneumonia.Methods The50children with bacterial pneumonia treated in our hospital from June2015to June2016were selected as the observation group,and50healthy children who were examined in our hospital duringthe same period were selected as the control group.The levels of PCT,IL-6,IL-8,TNF-αand hs-CRP in twogroups were detected and compared.Results The indexes of the observation group were obviously higher thanthose of the control group(P<0.05).Conclusion The clinical effects of serum PCT,IL-6,IL-8,TNF-αand hs-CRPlevels in the detection of bacterial pneumonia in children is obvious,and it is worthy of clinical promotion.