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腹腔镜手术不同CO_2气腹压力对机体炎性细胞因子的影响研究 被引量:2

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摘要 选取我院96例行腹腔镜手术患者,依照随机数字表法分为A组、B组及C组各32例。A组、B组、C组于麻醉成功后分别以10mm Hg、12mm Hg、15mm Hg气腹压力创建CO2气腹施行手术。分别在麻醉成功后、气腹创建后、手术完毕后、术后24h采集各组外周静脉血,检测并对比各组肿瘤坏死因子α(TNF-α)、白介素-6(IL-6)、白介素-1β(IL-β)水平。结果 3组术前TNF-α、IL-6、IL-β水平相比,差异无统计学意义(P>0.05);三组气腹创建后、手术完毕后的TNF-α、IL-6、IL-β水平均较术前上升,且C组上述指标水平上升幅度大于A组、B组,差异具有统计学意义(P<0.05);三组在术后24h TNF-α、IL-6、IL-β水平均有所下降,组间对比差异无统计学意义(P>0.05)。TNF-α、IL-6、IL-β等炎性细胞因子水平和气腹压力高低之间存在明显正相关,在行腹腔镜手术时应用低气腹压力有助于降低患者应激反应水平及机体创伤程度。
出处 《现代诊断与治疗》 CAS 2017年第15期2843-2845,共3页 Modern Diagnosis and Treatment
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