当归拈痛丸治疗痛风性肾病疗效及对血肌酐、尿素氮水平影响

Clinical effects and influence on serum creatinine and blood urea nitrogen of Danggui Niantong pill in treatment of gouty nephropathy

目的分析当归拈痛丸治疗痛风性肾病疗效及对血肌酐、尿素氮水平影响。方法将80例痛风性肾病患者随机分组，各40例。对照组给予一般疗法，观察组另外给予当归拈痛丸。结果观察组总有效率为92.50%，高于对照组72.50%（P＜0.05）。治疗后，观察组肾功能血清指标和尿液相关因子指标均低于对照组（P＜0.05），血沉（ESR）、白细胞（WBC）和中性粒细胞（N）均低于对照组（P＜0.05）。观察组不良反应率为15.00%，和对照组的12.50%相比，差异无统计学意义。结论当归拈痛丸可提高痛风性肾病的治疗效果，降低肾功能损害，且较安全。

Objective To analyse clinical effects and influence on serum creatinine and blood urea nitrogen of Danggui Niantong pill intreatment of gouty nephropathy.Methods80patients with gouty nephropathy were divided into two groups and each with40cases.The controlgroup were treated with general therapy,and observation group was treated another with Danggui Niantong pill.Results After treatment,effectiverate of observation group was92.50%,higher than that of control group72.50%(P<0.05).After treatment,renal function serum markers and urinerelated factors level of observation group were lower than control group(P<0.05).ESR,WBC and N level of observation group were lower thanthat of control group(P<0.05).The proportion of adverse reactions of observation group was15.00%and control group was12.50%.ConclusionDanggui Niantong pill can improve clinical effects of gouty nephropathy,reduce renal damage amd does not increase adverse reactions.