静脉注射左西孟旦治疗心脏手术后急性心功能衰竭效果探讨

Effect of intravenous injection of levosimendan on acute heart failure after cardiac surgery

目的探讨和分析静脉注射左西孟旦治疗心脏手术后急性心功能衰竭效果。方法选取本院在2014年3月～2017年3月之间接受心脏手术治疗后急性心功能衰竭患者80例进行本次的研究，对患者在进行治疗前以及治疗后24h的心率、左心室射血分数、平均动脉压以及中心静脉压等相关指标进行监测。结果所有患者中有58例患者在接受治疗后存活，22例患者在治疗过程中或者治疗后死亡。与治疗前相比，患者在治疗后24h的左心室射血分数、中心静脉、平均动脉压以及心率的变化情况均有明显的改善，2组之间的数据相比较差异具有统计学意义（P＜0.05）。有8例患者在治疗过程中出现了短暂性的血压降低的情况，但是在采取相应措施之后症状消失，其他的患者均没有发生较为严重的不良反应症状。结论针对接受心脏手术治疗后急性心功能衰竭的患者实施静脉注射左西孟旦治疗的方法能够使患者的心脏功能得到有效的改善，对患者的预后有重要的影响作用，应该价值相对较高。

Objective To investigate and analyze the efficacy of intravenous levosimendan in the treatment of acute cardiac failure aftercardiac surgery.Methods The study of the80cases of acute heart failure in patients undergoing cardiac surgery after treatment in March2014toMarch2017,the patients were monitored in the treatment before and after treatment of24h heart rate,left ventricular ejection fraction,mean arterialpressure and central venous pressure and other related indicators.Results Of all patients,58survived after treatment,and22died during or aftertreatment.Compared with before treatment,after treatment of24h in left ventricular ejection fraction in patients,mean arterial pressure,centralvenous and changes in heart rate were significantly improved,data between the two groups had significant difference compared with statisticalsignificance(P<0.05).In8patients,transient blood pressure reduction occurred during treatment,but symptoms disappeared after taking appropriatemeasures,and other patients had no more severe adverse reactions.Conclusion According to the method of intravenous levosimendan in treatment ofacute heart failure in patients undergoing cardiac surgery after treatment can make the patient’s cardiac function improved,has a significant effect onthe prognosis of patients,should have a relatively high value.