综合呼吸功能锻炼联合药物治疗对促进肺癌患者术后快速康复的作用

Effect of combined respiratory function combined with drug therapy on rapid recovery of lung cancer patients

目的探讨综合呼吸功能锻炼联合药物治疗在促进肺癌患者术后快速康复中的作用，为临床治疗提供参考依据。方法选取本院2012年1月～2015年12月收治的拟行手术治疗并经病理学诊断为早期非小细胞肺癌患者40例作为研究对象，按入院先后顺序将其分为干预组和对照组，每组20例。所有患者均在肺癌常规化疗基础上给予盐酸埃克替尼治疗，并实施常规围术期护理，干预组在其基础上接受综合呼吸功能锻炼，主要有心理护理、健康教育、围术期呼吸功能锻炼等。比较2组患者术后肺部并发症发生情况、生存质量改善情况和术后康复情况。结果干预组术后肺部并发症发生率为5%（1/20，仅肺炎1例），对照组术后肺部并发症发生率为35%（7/20，肺炎4例，肺不张2例，低氧血症1例），干预组术后肺部并发症发生率明显低于对照组（P＜0.05）。干预组SF-36各维度评分均高于对照组，比较差异均有统计学意义（P＜0.05）。干预组拔管时间和术后住院时间均短于对照组，6分钟步行试验（6MWK）长于对照组，比较差异均有统计学意义（P＜0.05）。结论综合呼吸功能锻炼联合盐酸埃克替尼治疗可减少早期非小细胞肺癌患者术后肺部并发症，改善其生存质量，促进术后快速康复。

Objective To explore the role of combined respiratory function combined with drug therapy in the rapid recovery of lung cancerpatients,and to provide reference for clinical treatment.Methods Forty patients with early non-small cell lung cancer(NSCLC)who underwentsurgical treatment from January2012to December2015were selected as subjects and were randomly divided into intervention group and controlgroup(n=20)according to the order of admission.All patients were treated with routine chemotherapy on the basis of routine chemotherapyof lung cancer,and routine perioperative care was carried out.The intervention group received comprehensive respiratory function exercise onthe basis of them.There were psychological nursing,health education,perioperative respiratory function exercise and so on.The incidence ofpostoperative pulmonary complications,quality of life improvement and postoperative rehabilitation were compared between the two groups.Results The incidence of pulmonary complications in the intervention group was5%(1/20,only one case of pneumonia),the incidence ofpulmonary complications in the control group was35%(7/20,4cases of pneumonia,two cases of atelectasis,one case of hypoxemia),the incidenceof postoperative pulmonary complications in the intervention group was significantly lower than that in the control group(P<0.05).The scores of SF-36in the intervention group were higher than those in the control group,the difference was statistically significant(P<0.05).The extubation time andpostoperative hospital stay in the intervention group were shorter than in the control group.The6-minute walking test(6MWK)was longer than thecontrol group,the difference was statistically significant(P<0.05).Conclusion Comprehensive respiratory function combined with treatment withetestin hydrochloride can reduce the early postoperative pulmonary complications in patients with early non-small cell lung cancer,improve its qualityof life and promote rapid postoperative rehabilitation.