舒芬太尼与瑞芬太尼复合丙泊酚全凭静脉麻醉用于神经外科手术效果与安全性的系统评价

Systematic review of the effect and safety of sufentanil and remifentanil combined with propofol for total intravenous anesthesia in department of neurosurgery operation

目的:探讨舒芬太尼与瑞芬太尼复合丙泊酚全凭静脉麻醉用于神经外科的手术效果与安全性。方法:选择神经外科患者60例,随机分为对照组和观察组。对照组采用瑞芬太尼复合丙泊酚麻醉,观察组采用舒芬太尼复合丙泊酚麻醉,比较两组麻醉效果。结果:对照组苏醒时间、拔管时间均明显少于观察组(P<0.05);观察组疼痛程度明显轻于对照组(P<0.05)。结论:瑞芬太尼和舒芬太尼对患者的麻醉效果均较好,瑞芬太尼能加快患者苏醒,舒芬太尼能明显减轻患者痛苦。

Objective:To explore the effect and safety of sufentanil and remifentanil combined with propofol for total intravenousanesthesia in department of neurosurgery operation.Methods:60patients in department of neurosurgery were selected.They wererandomly divided into the control group and the observation group.The control group was given remifentanil combined withpropofol anesthesia,and the observation group was given sufentanil combined with propofol anesthesia.We compared theanesthetic effects between groups.Results:In the control group,the recovery time and extubation time were significantly less thanthose in the observation group(P<0.05);the degree of pain in the observation group was significantly lighter than the controlgroup(P<0.05).Conclusion:The anesthetic effects of remifentanil and sufentanil were all better.Remifentanil can accelerate therecovery of patients,and sufentanil can obviously alleviate the pain of patients.