婴儿瘰疬性苔藓5例

Five cases of infants lichen scrofulosorum

目的总结5例婴儿瘰疬性苔藓的临床和病理特点。方法回顾性分析2015年至2016年于北京儿童医院皮肤科门诊就诊的5例婴儿瘰疬性苔藓患者的临床和病理资料。结果 5例患儿均为卡介苗接种后表现为躯干和(或)四肢皮色至淡红色毛囊性小丘疹,表面附着少许鳞屑。5例患儿行结核分枝杆菌感染和免疫功能筛查均为阴性。皮肤病理提示为真皮上部毛囊或汗管周围上皮样肉芽肿,可见上皮样细胞及少许郎罕巨细胞,周围有淋巴细胞浸润。结论 5例患儿随访半年,皮损自然消退,未给予任何治疗。仅1例患儿前胸遗留少许炎症后色素沉着。

Objective To investigate the clinical and pathological characteristics of five infants with lichen scrofulosorum(LS).Methods The clinical and pathological data of5outpatients of infants with LS who were admitted to Beijing Children's Hospital,Capital Medical University from2015to2016were analyzed,retrospectively.Results After receiving Bacillus Calmette Guerin(BCG)vaccinations,all patients presented with tiny,skin-coloured to erythematous perifollicular papules over the trunk and extremities,with scales on the surface.All5patients showed negative results for tuberculosis infection and immune deficiency tests.Histopathologic examination of5patients showed distinctive features,including the epidermal granuloma in the upper-dermis,usually in the vicinity of hair follicles and suboriferous,which were composed of epithelioid cells with a few Langhans giant cells and lymphocytes at the periphery.Conclusions Lichen scrofulosorum of5patients resolved spontaneously in half a year without any treatment,excluding1case with hyperpigmentation on the chest.