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早产儿坏死性小肠结肠炎的危险因素分析 被引量:2

Analysis of risk factors of necrotizing enterocolitis in premature infants
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摘要 目的:探讨早产儿发生坏死性小肠结肠炎(NEC)的危险因素。方法:收治早产儿162例,分为NEC组和非NEC组,比较两组的临床资料。结果:两组性别、胎龄、出生体重、娩出方式差异无统计学意义(P>0.05)。NEC组住院时间明显长于非NEC组(P<0.05)。母亲子痫前期、新生儿窒息、输血、败血症和RDS是NEC发病的危险因素,而母亲产前糖皮质激素的使用是NEC发生的保护因素。结论:母亲子痫前期、新生儿窒息、输血、败血症和RDS可增加早产儿NEC的发病风险,而产前糖皮质激素的使用是NEC的保护因素。 Objective:To explore the risk factors of necrotizing enterocolitis(NEC)in premature infants.Methods:162cases ofpremature infants were selected.They were divided into the NEC group and the non NEC group.We compared the clinical data oftwo groups.Results:There were no significant differences between groups in gender,gestational age,birth weight and deliverymode(P>0.05).In the NEC group,the length of stay was significantly longer than the non NEC group(P<0.05).Pre eclampsia,asphyxia neonatorum,transfusion,sepsis and RDS were the risk factors of NEC,and prenatal glucocorticoid use was a protectivefactor for NEC.Conclusion:Pre eclampsia,asphyxia neonatorum,transfusion,sepsis and RDS can increase the risk of NEC inpremature infants,and prenatal glucocorticoid use was a protective factor for NEC.
作者 邓香 Deng Xiang(Department of Paediatrics,the Fifth People's Hospital of Chengdu City 611130)
出处 《中国社区医师》 2017年第29期35-36,共2页 Chinese Community Doctors
关键词 早产儿 坏死性小肠结肠炎 危险因素 Premature infants Necrotizing enterocolitis Risk factors
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  • 1Szajewska H, Mrukowicz J. Probiotics in the treatment and prevention of acute infectious diarrhea in infants and children:a systematic review of published randomized, double-blind, placebo controlled trials [J]. J Pediatr Gastroenterol Nutr, 2001,33 (Suppl 2 ) : 517-525.
  • 2Van Niel CW, Feudtner C, Garrison MM, et al. Lactobacillus therapy for acute infectious diarrhea in children: a meta-analysis [J]. Pediatrics,2002,109(4) :678-684.
  • 3Allen SJ, Okoko B, Martinez E, et al. Probiotics for treating infectious diarrhoea [DB/OL]. Cochrane Database Syst Rev,2004(2) :CD003048.
  • 4Bartlett JG, Chang TW, Gurwith M, et al. Antibioticassociated pseudomembranous colitis due to toxin-producing clostridia [J]. N Engl J Med,1978,298(10): 531-534.
  • 5Tankanow RM,Ross MB,Ertel IJ,et al. A double-blind, placebo-controlled study of the efficacy of Lactinex in the prophylaxis of amoxicillin-induced diarrhea [J]. DICP , 1990,24(2) :382-384.
  • 6Jirapinyo P, Densupsoontorn N ,Thamonsiri N ,et al. Prevention of antibiotic-associated diarrhea in infants by probiotics [J]. J Med Assoc Thai,2002,85 (Suppl 2): s739-s742.
  • 7Vanderhoof JA, Whitney DB, Antonson DL, et al. Lactobacillus GG in the prevention of antibiotic-associated diarrhea in children [J]. J Pediatr, 1999,135 (5) :564-568.
  • 8Kotowska M, Albrecht P, Szajewska H. Saccharomyces boulardii in the prevention of antibiotic-associated diarrhea in children : a randomized double-blind placebo-controlled trial [J]. Aliment Pharmacol Ther,2005,21 (5): 583-590.
  • 9Correa NB, Peret Filho LA, Penna FJ, et al. A randomized formula controlled trial of Bifidobacterium lactis and Streptococcus thermophilus for prevention of antibioticassociated diarrhea in infants [J]. J Clin Gastroenterol, 2005,39 (5) :385-389.
  • 10Ford-Jones EL, Mindorff CM, Gold R, et al. The incidence of viral-associated diarrhea after admission to a pediatric hospital [J]. Am J Epidemiol, 1990,131(4) : 711-718.

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