颈动脉狭窄患者颈部CTA不同斑块成分厚度和性质及其与脑梗死或短暂性脑缺血发作的相关性分析

A correlation analysis between the thickness and property of different plaques in neck CTA and cerebral infarction or TIA for patients with carotid artery stenosis

目的:探究颈动脉狭窄患者颈部CT血管成像(CTA)显示的不同斑块成分的厚度和性质,并分析其与脑梗死或短暂性脑缺血发作(TIA)的相关性。方法:选取医院收治的160例颈动脉狭窄患者,将发生过脑血管事件的患者纳入观察组(103例),未发生过脑血管事件的患者纳入对照组(57例)。对所有患者进行颈部CTA扫描后测量其图像上不同斑块成分的厚度和软斑内的CT值,并分析这些斑块的特征与发生脑梗死或TIA的相关性。结果:观察组与对照组比较,其患者的软斑厚度明显较大,硬斑厚度明显较小,两组比较差异有统计学意义(t=5.704,t=8.139;P<0.05);经logistic回归分析显示,颈动脉狭窄患者颈部CTA表现中软斑的厚度与患者脑梗死或TIA事件的发生具有一定的相关性(r=0.926,P<0.05)。结论:颈动脉狭窄患者脑梗死或TIA事件的发生与颈部CTA表现中软斑的厚度具有一定的相关性,临床上可以通过测量颈动脉软斑的厚度预估脑梗死或TIA事件的发生,达到预防和治疗的目的。

Objective:To explore the thickness and property of different plaques in neckcomputed tomography angiography(CTA)for the patients with carotid artery stenosis,and analyze the correlation between them and cerebral infarction or transient ischemicattack(TIA).Methods:160patients with carotid artery stenosis were divided into observation group(103cases)and control group(57cases)according to whether they had occurred cerebrovascular events.Through CTA for neckof patients to measure the thickness of different plaques and CT value in mild plaque in the image,and analyzethe characteristic of these plaques and the correlation between them and cerebral infarction or TIA.Results:Thethickness of mild plaque of observation group was significantly thicker than that of control group while the situationof thickness of hard plague was just statistically adverse.The results of analysis of regression indicated that therewas a certain correlation between thickness of mild plaque and cerebral infarction or TIA event(r=0.926,P<0.05).Conclusion:There was a certain correlation between thickness of mild plaque in neck CTA and cerebral infarctionor TIA event in patients with carotid artery stenosis.In clinical practice,the occurrence of cerebral infarction orTIA event can be forecasted through measure thickness of mild plaque of carotid artery,so as to achieve the aims ofprevention and treatment for them.