2种血液保存液对新鲜冰冻血浆Ⅷ因子含量影响分析

Effect of Two Kinds of Blood Preservative Solution on the Content of Factor Ⅷ Recovery in Fresh Frozen Plasma

目的探讨采用CPDA、ACD-B血液保存液的全血分离制备的新鲜冰冻血浆(FFP)中Ⅷ含量的差异并分析其相关因素。方法随机抽取用CPDA(A组)、ACD-B(B组)保存的标量400 ml全血所分离制备的FFP各48份,测定FⅧ含量,比较2组FⅧ均值及合格率。结果 2组FⅧ含量的差异无统计学意义(P>0.05),B组较A组FⅧ达到质量标准数量的合格率明显下降。结论 ACD-B组FⅧ含量达到质量标准数量的下降与保存液容量增多所致稀释性浓度下降、实际采血量等因素有关。

Objective To investigate the fresh frozen plasma(FFP)VIII derived from the whole blood with CPDA or ACD-B blood preservative solution,content difference and analyze the relative factors.Methods48cases of FVIII derived from the whole blood with CPDA(A group)or ACD-B(B group)blood preservative solution were randomized for the determination respectively,compared the two groups of the mean value and qualified rate of FVIII.Results There was no significant difference between the2groups of FVIII content(P>0.05),compared with the A group,the qualified rate of FVIII quality standards in B group decreased significantly.Conclusion The decline of qualified rate of FVIII quality standards in B group related to the related factors such as the decrease of the concentration of dilution caused by the increase of the liquid storage capacity,the actual blood collection and so on.