急性脑梗死合并H型高血压患者经颅多普勒超声血流动力学分型的临床意义

The clinical significance of transcranial Doppler flow grade for patients with acute cerebral infarction combined with H type hypertension

目的:探讨急性脑梗死合并H型高血压患者经颅多普勒超声血流动力学分型的临床意义。方法:选取医院收治的92例急性脑梗死合并H型高血压患者纳入观察组,同期选取78例非H型高血压的急性脑梗死患者纳入对照组。对比两组患者临床特征差异;分析急性脑梗死合并H型高血压经颅多普勒超声血流动力学分型与美国国立卫生研究院卒中量表(NIHSS)评分的相关性。结果:经颅多普勒超声血流动力学分型中观察组0级的患者为10.87%,显著高于对照组患者的1.28%,两组比较差异有统计学意义(x2=4.925,P<0.05);观察组分型5级的患者为6.52%,低于对照组患者的21.79%,两组比较差异有统计学意义(x2=8.417,P<0.05);观察组收缩期和舒张期血流速度显著降低,两组比较差异有统计学意义(t=3.645,t=5.251;P<0.05);观察组脑梗死面积显著增加,两组比较差异有统计学意义(t=4.405,P=0.000);观察组NIHSS评分显著增加,两组比较差异有统计学意义(t=2.688,P<0.05)。Pearson线性相关性分析显示H型高血压的脑梗死患者血流动力学分型与NIHSS显著负相关(r=-0.284,P<0.05)。结论:经颅多普勒超声血流动力学分型可以较好地区分合并H型高血压的急性脑梗死患者病情严重程度。

Objective:To explore the clinical significance of transcranial Doppler flow grades for patients with acute cerebral infarction combined with H type hypertension.Methods:92patients with acute cerebral infarction combined with H type hypertension were divided into observation group,and78patients with acute cerebral infarction were divided into control group during the same period.The differences of the two groups were compared and researched.The correlation between transcranial Doppler flow grade of acute cerebral infarction combined with H type hypertension and the score of NIHSS was compared and analyzed.Results:As the results of transcranial Doppler flow grades,the ratio of the patients in0grade was10.87%in observation group,and it was significantly higher than that of control group(1.28%)(x2=4.925,P<0.05).The ratio of the patients in5grade was6.52%in observation group,and it was significantly lower than that of control group(21.79%)(x2=8.417,P<0.05).The blood flow velocities of systole and diastole of observation group were significantly lower than that of control group(t=3.645,t=5.251,P<0.05),respectively.The cerebral infarct size of observation group was significantly larger than that of control(t=4.405,P<0.05).The score of NIHSS of observation group was significantly higher thanthat of control group(t=2.688,P<0.05).The results of Pearson linear correlation analysisindicated that there was a significantly negative correlation between transcranial Doppler flow grades and NIHSS(r=-0.284,P<0.05).Conclusion:The transcranial Doppler flow grades can identify the order of severity for patients with acute cerebral infarction combined with H type hypertension.