免疫质谱技术及其临床研究应用进展

Advances in immune mass spectrometry and its clinical application

免疫质谱技术是新近发展起来的联合抗体分离技术与生物质谱技术的一种分析技术,除具有传统的放射免疫技术、酶免疫技术和荧光免疫技术的高特异、高灵敏和质谱技术的高通量特点外,还具有分辨修饰和变异的高度精确性。在肿瘤、自身免疫病、代谢性疾病和退行性疾病等的诊断、病情监测和疗效判断等方面都将有广阔的应用前景。

Immunologic spectrometry is a newly developed technology with combination of antibody isolation and biological mass spectrometry.It has the merits including high specificity and highsensitivity that are similar to traditional radioimmunoassay,enzyme immunoassay and fluorescence immunity technology.It is also a high-throughput technology that is simitar to mass spectrometry.Immuologic mass spectrometry also posesses highle accuracy and resotation for modification and variation.It will have a broad application in tumor,autoimmune diseases,metabolic diseases and degenerative diseases diagnosis,disease monitoring and curative efficact judgments,etc.