活血化瘀方对髋部骨折早期血液流变学的影响

Efficacy of the Huoxue Huayu decoction on hemorheology in early hip fracture

目的:探讨活血化瘀方对髋部骨折早期血液流变学的干预作用。方法:将96例髋部骨折早期患者随机分为两组,对照组48例在骨折早期采用西医常规对症处理,中药组48例在骨折早期配合活血化瘀方,观察两组治疗前、治疗7d后的血液流变学指标(全血黏稠度、血浆黏度、红细胞压积)的变化情况。结果:中药组、对照组术前各指标比较,差异无统计学意义(P>0.05),具有可比性;对照组患者治疗7d后血液流变学指标较治疗前下降,但差异无统计学意义(P>0.05),中药组患者治疗7d后与治疗前比较,差异有统计学意义(P<0.05),且中药组治疗7d后各指标较对照组下降,差异有统计学意义(P<0.05)。结论:活血化瘀方对髋部骨折早期血液流变学指标具有一定的改善效果,说明在髋部骨折早期活血化瘀方可有效改善血液的高黏、高凝状态。

Objective:To study the effect of the Huoxue Huayu decoction on hemorheology in early hip fracture.Methods:96patients were randomly divided into two groups.The control group(48cases)was treated with conventional western medicine.The TCM medicine group(48cases)was treated with the Huoxue Huayu decoction.Results:There was no significant difference between the groups before treatment(P>0.05).Compared with before treatment,the hemorheological indexes in the control group were decreased in7days(P>0.05);and those in the TCM medicine group was lower than before treatment and the control group in7days(P<0.05).Conclusion:The Huoxue Huayu decoction was effective on hemorheological indexes in early hip fracture,by effectively improving the high viscosity and hypercoagulable state of blood.