木丹颗粒治疗糖尿病周围神经病变的临床疗效及安全性分析

Safety analysis and clinical efficiency of the Mudan granules on DPN

目的:观察木丹颗粒治疗糖尿病周围神经病变的临床疗效及其安全性。方法:将接受治疗的120例糖尿病周围神经病变患者随机分成三组,对照组、试验A组和试验B组各40例。对照组单独给予甲钴胺片治疗,试验A组给予木丹颗粒治疗,实验B组给予甲钴胺片联合木丹颗粒治疗,观察记录三组的临床疗效。结果:对照组总有效率为85%,试验A组总有效率为80%,试验B组总有效率为95%。对照组与试验A组结果比较,P>0.05,无显著性差异;对照组与试验B组结果比较,P<0.05;实验A组与实验B组结果比较,P<0.05,有显著性差异。结论:木丹颗粒及甲钴胺单独治疗糖尿病周围神经病变疗效确切,而木丹颗粒联合甲钴胺片治疗糖尿病周围神经病变疗效更显著,且安全性高,是治疗糖尿病周围神经病变较为有效的途径,值得临床推广使用。

Objective:To observe the clinical efficacy and safety of the Mudan granules on diabetic peripheral neuropathy.Methods:120patients were randomly divided into the control group,experimental group A and group B,40cases in each group.The control group was treated with mecobalamin tablets.The experimental group A was treated with the Mudan granules;and the experimental group B was treated with mecobalamin tablets and the Mudan granule.Results:The total efficiency was85%in the control group,80%in the experimental group A,and95%in the experimental group B.There was no significant difference between the control group and the experimental group A.There was a significant difference between the control group and the experimental group B,P<0.05.There was a significant difference between the experimental group A and B,P<0.05.Conclusion:The Mudan granules plus mecobalamin were more effective on diabetic peripheral neuropathy,with safety,and is worthy of promotion.