地西泮与苯巴比妥钠预防小儿高热惊厥复发100例临床对比建议

Clinical recommendations of diazepam and phenobarbital sodium in prevention and treatment of100children with febrile seizure relapse

目的探究对小儿高热惊厥患病儿童应用地西泮与苯巴比妥钠治疗方式实施救治的临床治疗结果及其对病症复发情况的预防疗效。方法选取2016年4月～2017年8月青田县人民医院接收诊治的小儿高热惊厥患病儿童100例作为研究样本，均为本院依据相关标准确诊的小儿高热惊厥患病儿童。并将其随机分为对照组和观察组，每组50例。首先给予全部患病儿童常规基础性治疗方式，随后在此基础上对照组患病儿童给予地西泮展开治疗过程，观察组采取苯巴比妥钠治疗方式实施救治。观察并比较2组患病儿童临床治疗结果、临床表征的改善时间、治愈的平均时间、惊厥复发率、血钾血钠等相关生理指标的变化情况、患病儿童及其家属对治疗模式的满意程度。结果治疗后，观察组患病儿童的临床治疗结果显著优于对照组（P＜0.05）；观察组患病儿童的退热时间及惊厥消失时间与对照组对应的时间数值相比，均有明显缩短迹象（P＜0.05）；观察组患病儿童治愈的平均时间相较于对照组对应数值，缩短趋势显著（P＜0.05）；观察组患病儿童的惊厥复发率为8.00%，相较于对照组对应数值24.00%，下降趋势显著（P＜0.05）；观察组患病儿童的血钾血钠等相关生理指标的变化情况显著优于对照组对应数值（P＜0.05）；观察组患病儿童及其家属对治疗模式的满意程度为94.00%，相较于对照组84.00%，提升趋势显著（P＜0.05）。结论对小儿高热惊厥患病儿童应用地西泮与苯巴比妥钠治疗方式实施救治，临床治疗结果显著，有助于减少惊厥复发情况出现的可能性，缩短了症状的改善时间及治愈的平均时间，对患病儿童及其家属对治疗模式满意程度的提升具有积极的促进作用。

Objective To explore the clinical treatment of children with febrile seizures in children with diazepam and phenobarbital sodium treatment and treatment of the results of its prevention and treatment of disease recurrence.Methods From April2016to August2017,100cases of pediatric febrile seizures in our hospital were selected as research samples,all of which were diagnosed as children with febrile seizures in our hospital according to relevant standards.And they were randomly divided into two groups,control group and observation group,50cases in each group.First of all,given to all children with conventional basic treatment,then on the basis of the control group of children given diazepam treatment process,the observation group to take phenobarbital sodium treatment for treatment.To observe and compare the results of clinical treatment in two groups of children,clinical signs of improvement,the average time to cure,the recurrence rate of seizures,serum and serum sodium and other related physiological changes,the sick children and their families satisfied with the treatment model degree.Results After treatment,the results of clinical treatment of the sick children in the observation group were significantly better than those in the control group(P<0.05).Compared with the control group,both the antipyretic time and the disappearance time of the convulsions in the sick children in the observation group(P<0.05).The average cure time of the children in the observation group was shorter than that of the control group(P<0.05),and the recurrence rate of the convulsion in the observation group was8.00%(P<0.05).Compared with the control group,the change trend of serum potassium,sodium and other related physiological indexes was significantly better than that of the control group(P<0.05).The observation group The degree of satisfaction of the sick children and their relatives to the treatment model was94.00%,which was significantly higher than that of the control group(84.00%,P<0.05).Conclusion Children with febrile seizures in children with diazepam and phenobarbital sodium treatment for the implementation of treatment,the results of a significant clinical treatment can help reduce the possibility of recurrence of seizures,shorten the time to improve symptoms and the average time to cure,Has a positive role in promoting the satisfaction of the treatment model to the sick children and their families.