影响乳腺癌术中冰冻诊断准确性的病理与临床因素分析

Analyze on the pathologic and clinical factors influencing the accuracy of intraoperative frozen diagnosis of breast cancer

目的分析影响乳腺癌术中冰冻诊断准确性的病理与临床因素。方法选取宁波市鄞州区第二人民医院2014年5月～2017年6月收治的170例乳腺癌手术患者的临床资料，将其冰冻诊断结果与专业乳腺癌诊断分级进行比较，然后对比其诊断准确性，并对比分析影响诊断结果的相关临床因素与病理因素。结果患者的术中冰冻切片诊断准确性和术后诊断结果一致性中等，Kappa=0.59，准确性为67.06%，通过Logistic线性回归计算分析后发现，影响乳腺癌患者术中冰冻诊断正确性的因素为肿瘤钙化程度、年龄情况、肿瘤大小以及病理分级。结论对乳腺癌手术患者冰冻诊断准确性造成影响的因素具有一定的复杂性，在对患者进行诊断的时候应注意相关因素的影响。

Objective To analyze the pathology and clinical factors that affect the accuracy of frozen diagnosis in breast cancer.Methods170cases were selected from the clinical data of breast cancer patients treated in our hospital from May2014to June2017.The results of frozen diagnosis were compared with the diagnosis and classification of breast cancer.Then,the diagnostic accuracy was compared with the analysis diagnostic results of the relevant clinical factors and pathological factors.Results The accuracy of intraoperative frozen section diagnosis and the consistency of the results were moderate,Kappa=0.59,the accuracy of67.06%,calculated by logistic linear regression analysis found that the impact of breast cancer in patients with frozen diagnosis of correctness Factors were tumor calcification,age,tumor size,and pathological grade.Conclusion The factors influencing the accuracy of frozen diagnosis in patients with breast cancer have certain complexity.Therefore,we should pay attention to the influence of relevant factors when diagnosing the patients,so as to further improve the diagnostic accuracy so as to be effective for follow-up treatment.