药学干预对抗生素临床合理应用的影响分析

Analysis of the influence of pharmaceutical intervention on the rational use of antibiotics

目的探讨药学干预对抗生素临床合理应用的具体影响效果。方法2015年台州市中医院抗生素使用情况未实施药学干预措施，2016年初通过借鉴兄弟单位相关经验、查阅临床资料并结合自身实际情况引入药学干预措施并应用于临床抗生素使用过程中，记录各年度抗生素临床使用合理情况。结果2015年台州市中医院11137张涉及抗生素处方中抗生素不合理利用率高达17.07%，2016年11450张涉及抗生素处方中抗生素不合理利用率仅为1.60%，2年比较差异具有统计学意义（P＜0.05）。结论应用药学干预措施可显著提高临床抗生素合理使用率，有利于保障患者临床疾病治疗有效性、安全性。

Objective To investigate the effect of pharmaceutical intervention on the rational use of antibiotics.Methods The use of antibiotics in Taizhou Traditional Chinese Medicine Hospital in2015without the implementation of pharmaceutical interventions in early2016by the brothers from the unit of relevant experience,access to clinical data according to their own situation to introduce pharmaceutical interventions and clinical application of antibiotics in the process of recording,rational use of antibiotics in our hospital each year of clinical.Results The irrational utilization rate of antibiotics in11137antibiotic prescriptions in2015was as high as17.07%.In2016,the irrational utilization rate of antibiotics in11450antibiotics involved was only1.60%,there wassignificantdifferencein two years(P<0.05).Conclusion The application of pharmaceutical intervention measures can significantly improve the rational use rate of clinical antibiotics,and is conducive to ensuring the effectiveness and safety of clinical treatment of patients.