江苏省阜宁县农村50岁及以上人群年龄相关性黄斑变性的流行病学调查

Epidemiological survey of age-related macular degeneration in population aged ≥ 50 years in Funing county,Jiangsu

目的:分析江苏省阜宁县50岁及以上农村人群中年龄相关性黄斑变性(age-related macular degeneration,ARMD)的患病率情况。方法:本项调查研究采用随机整群抽样的方法,在江苏省盐城阜宁县设置30个调查点,对50岁及以上农村人群进行视力和眼部相关检查。计量资料采用均数±标准差表示,组间比较采用独立样本t检验;计数资料采用率或构成比表示,组间比较采用χ~2检验。应用Logistic回归分析法分析年龄、性别等因素对ARMD患病率的影响。结果:随机抽样6145例,实际纳入5947例,受检率为96.78%。检出ARMD患者448例633眼,患病率为7.53%。按日常生活视力(PVA)和视力损伤标准计算,在中重度视力损伤和盲眼中,由ARMD引起的中重度视力损失和盲分别占11.96%和4.13%;按最佳矫正视力(BCVA)和视力损伤标准计算,在中重度视力损伤和盲眼中,由ARMD引起的中重度视力损伤和盲分别占7.79%和4.45%。高龄是影响ARMD的相关因素(OR=1.01,P=0.040)。结论:江苏省阜宁县农村50岁及以上人群中,ARMD患病率较高,是影响老年人视力的主要原因之一。

AIM:To investigate the prevalence of age-related macular degeneration(ARMD)among people aged50years and above in Funing county,Jiangsu province.METHODS:Survey research.Random cluster sampling was used in selecting individuals aged50years in30clusters in Funing county.Proportions were compared by using the test and the means compared by using the t-test.Logistic regression was used to detect possible factors of ARMDsuchasageandgender.RESULTS:A total of6145persons aged50years were enumerated and5947(96.78%)participants were received visual acuity test and eye examination.The prevalence of ARMD was7.53%,with a total of448individuals(633eyes).The prevalence of blindness and visual impairment for presenting visual acuity were4.13%and11.96%,respectively.The prevalence of blindness and visual impairment for presenting visual acuity were4.45%and7.79%,respectively.Older were significant risk factors of ARMD(OR=1.01,P=0.04).CONCLUSION:The prevalence of ARMD was higher among people aged50years and above in Funing county,Jiangsu province.ARMD is one of the leading cause of visual impairment.