脑室腹腔分流术治疗正常颅压脑积水的疗效分析

Clinical Observation on Ventriculoperitoneal Shunt in the Treatment of Normal Pressure Hydrocephalus

目的观察脑室腹腔分流术治疗正常颅压脑积水的疗效。方法选取20例正常颅压脑积水病人,随机分为对照组、观察组,分别采用腰椎腹腔分流术、脑室腹腔分流术进行治疗,对比分析两组病人治疗后脑脊液压力、日常生活能力、精神状态、远期生活质量评分及并发症发生率。结果观察组手术前、手术中、手术后脑脊液压力与对照组比较差异无统计学意义(P>0.05);观察组治疗后日常生活能力评定量表(ADL)、简易智能精神状态检查量表(MMSE)、远期生活质量评分量表(KPS)评分明显优于对照组(P<0.05);观察组治疗后并发症发生率低于对照组(P<0.05)。结论脑室腹腔分流术治疗正常颅压脑积水的疗效较好,与腰椎腹腔分流术相比优势显著,可改善生活质量,降低并发症发生率。

Objective To explore the curative effect of ventriculoperitoneal shunt in the treatment for normal pressure hydrocephalus.Methods Twenty patients with normal cranial hydrocephalus in our hospital were randomly divided into control group and observa-tion group.And they were given lumbar peritoneal shunt and ventriculoperitoneal shunt for treatment,respectively.The cerebrospinalfluid pressure and daily life ability,mental state,quality life score of long term and complication rate of the two groups after treatmentwere compared.Results There was no significant difference in cerebrospinal fluid pressure between observation group and controlgroup during the surgical treatment and after surgical treatment(P>0.05).The scores of the activity of daily living(ADL),Mini Men-tal Status Exam(MMSE)and KPS in observation group after treatment were significantly higher than those in control group(P<0.05).The incidence of complications in observation group was significantly lower than that in the control group(P<0.05).ConclusionThe ventriculoperitoneal shunt in the treatment for normal pressure hydrocephalus can improve the quality of life,reduce the inci-dence of complications,which is better than that of surgery of Lumbar peritoneal shunt.