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羟考酮预处理对全身麻醉气管插管诱发患者眼内压升高的影响 被引量:1

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摘要 全身麻醉气管插管的伤害刺激程度大约为手术切皮时的1.5倍,不仅引起血压心率升高[1],而且可以导致眼内压升高[2-3],眼内压升高及其导致的眼球和视网膜灌注的降低压是术后视觉功能损伤的高危因素[4],全麻后视觉功能永久性损伤的发生率0.026%[5]。盐酸羟考酮注射液是阿片滋和资受体双重激动剂,其药理作用包括镇痛、抗焦虑、止咳、降低平滑肌张力等。研究[6]发现,羟考酮可有效抑制全身麻醉气管插管时的心血管反应,而对气管插管导致的应激性高眼内压的影响国内外鲜有报道。本研究探讨羟考酮预处理对气管插管时患者眼内压的影响。
出处 《浙江中西医结合杂志》 2017年第12期1065-1068,共4页 Zhejiang Journal of Integrated Traditional Chinese and Western Medicine
基金 浙江省湖州市卫生局科研基金项目(No.2015GY16)
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