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分化抑制因子2的生物学功能及其在乳腺癌中的研究进展 被引量:1

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摘要 分化抑制因子2(ID2)属螺旋-环-螺旋蛋白(HLH)的ID蛋白家族的一员,调控乳腺癌的上皮间质转化(EMT),并影响乳腺癌患者的预后。而ID2与HLH家族成员之间的协同作用形成了复杂的生物学调控网络,使其在乳腺癌中的生物学特性也复杂多变。笔者对ID2调控乳腺癌EMT的相关研究进行了综述。
出处 《中华乳腺病杂志(电子版)》 CAS CSCD 2016年第6期366-369,共4页 Chinese Journal of Breast Disease(Electronic Edition)
基金 国家重点基础研究发展计划(2011CB70770 973)
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