中药熏蒸联合海昆肾喜胶囊治疗慢性肾脏病临床观察

Clinical observation on treating chronic kidney disease by fumigation plus the Haikun Shenxi capsule

目的:探讨中药熏蒸疗法联合海昆肾喜胶囊延缓慢性肾脏病进展的临床疗效。方法:90例慢性肾脏病2-4期患者被随机分为对照组和治疗组,治疗组45例采用中药熏蒸疗法,同时口服海昆肾喜胶囊2粒,每日3次;对照组45例给予西医常规治疗,包括控制血压、血糖、血脂及对症处理,两组疗程均为30d。观察比较两组治疗前后血清肌酐(Scr)、尿素氮(BUN)、肾小球滤过率(GFR)、血红蛋白(Hb)、24h蛋白尿的变化以及患者的临床症状改善情况。结果:治疗组治疗后总有效率为86.7%,与对照组比较差异有统计学意义(P<0.05);治疗组治疗后Scr、BUN、GFR、Hb、24h蛋白尿水平与本组治疗前比较差异有统计学意义(P<0.05),与对照组治疗后比较差异有统计学意义(P<0.05);对照组治疗前后各项指标比较差异无统计学意义。结论:中药熏蒸疗法联合海昆肾喜胶囊可延缓慢性肾脏病进展,改善临床症状。

Objective:To investigate the clinical effect of fumigation plus the Haikun Shenxi capsule on chronic kidney disease.Methods:90cases of chronic kidney disease(period2to4)were randomly assigned to the treatment group and the control group;the treatment group was treated by fumigation with TCM medicine plus the Haikun Shenxi capsule,3times per day.The control group was treated with routine western medicine,including controlling blood pressure,blood glucose,blood lipid and symptomatic treatment.Results:After treatment,the total efficiency in the treatment group was86.7%,with a difference between the treatment group and control group(P<0.05).After treatment,Scr,BUN,GFR,Hb,24h proteinuria in the treatment group were better than before treatment and the control group(P<0.05).Conclusion:Fumigation of TCM medicine plus the Haikun Shenxi capsule can delay the progression of chronic kidney disease and improve symptoms.