112例烟雾病患者的临床表现和影像学特征分析

Clinical and imaging characteristics of 112 patients with moyamoya disease

目的研究烟雾病患者的临床表现和影像学的特征。方法回顾性分析112例烟雾病患者的临床症状及其影像学特征。结果本研究纳入112例成年人,其中男性40例(35.71%),女性72例(64.29%),年龄20~80岁,平均年龄为(47.21±11.05)岁,临床表现主要以出血型脑卒中及缺血型脑卒中两方面起病,并以出血型脑卒中多见(99例,88.39%),CT血管成像(CTA)、磁共振血管成像(MRA)及数字减影血管造影(DSA)结果均可发现清晰的颅底异常增生血管网。结论 (1)成人型烟雾病的发病高峰可能为40~50岁,女性多于男性;以出血型脑卒中多见,合并脑动脉瘤或动脉畸形可能是成人型烟雾病发生脑出血的病因;(2)CTA可以作为一种快速有效的初步筛查及早期诊断烟雾病的检查方法。

ObjectiveTo study the clinical and imaging characteristics of moyamoya disease.MethodsThe clinical symptoms and imaging characteristics of112patients with moyamoya disease were retrospectively analyzed.ResultsThe study included112cases of adults,40male cases(35.71%)and72female cases(64.29%).All112cases were aged20to80years(mean47.21±11.05years old).The main clinical manifestations were hemorrhagic stroke and ischemic stroke.The patients with hemorrhagic moyamoya disease were more common(99cases,88.39%).Abnormal proliferation of vascular network could be found by CT angiography(CTA),magnetic resonance angiography(MRA)and digital subtraction angiography(DSA).ConclusionsThe peak of adult moyamoya disease may be at the age of40to50years old,and the incidence of females was more than males.Hemorrhagic moyamoya disease was more common.Concomitant cerebral aneurysm or arteriovenous malformation may be the cause of intracerebral hemorrhage in adult moyamoya disease.CTA can be used as a rapid and effective method for early screening and early diagnosis of moyamoya disease.