醋酸去氨加压素联合雀啄灸治疗儿童原发性夜间遗尿症疗效观察

Clinical observation of desmopressin acetate combined with birdpecking moxibustion in the treatment of children with primary nocturnal enuresis

目的观察醋酸去氨加压素联合雀啄灸治疗儿童原发性夜间遗尿症的疗效和复发情况。方法2015年10月至2016年10月青岛大学附属威海市立第二医院儿科遗尿门诊收治原发性夜间遗尿症患儿81例,随机分为对照组40例和联合治疗组41例。对照组采用单一醋酸去氨加压素治疗,联合治疗组在对照组治疗基础上结合雀啄灸治疗。总疗程6个月。观察两组临床效果及不良反应,治疗结束后3个月随访复发情况。结果联合治疗组治疗有效率为73.2%(30/41),显著高于对照组45.0%(18/40),差异有统计学意义(P<0.05)。联合治疗组复发率为10.0%(3/30),显著低于对照组44.4%(8/18),差异有统计学意义(P<0.05)。两组患儿均未出现任何药物不良反应。结论醋酸去氨加压素联合雀啄灸治疗儿童原发性夜间遗尿症疗效较单一应用醋酸去氨加压素显著,且复发率明显降低,且药物不良反应少,可广泛应用于临床。

ObjectiveTo observe the clinical efficacy of desmopressin acetate combined with birdpecking moxibustion in the treatment of children with primary nocturnal enuresis and its recurrence.MethodsA total of81cases who were diagnosed as primary nocturnal enuresis were randomly divided into two groups:40cases were treated with simple acetic acid(control group)and41cases were treated with birdpecking moxibustion combined with acetic acid(combined treatment group).The treatment lasted for6months.Observe the clinical results and adverse reactions of the two groups.Follow up the recurrence during the3months after treatment.ResultsThe total effective rate of combined treatment group was73.2%(30/41),and in control group45.0%(18/40),there being significant difference between the two groups(P<0.05);the recurrence rate of combined treatment group was10.0%(3/30),significantly lower than the44.4%(8/18)of control group,the difference being statistically significant(P<0.05).There were no adverse reactions in both groups.ConclusionEffect of desmopressin acetate combined with birdpecking moxibustion in treating infantile primary nocturnal enuresis is significant with low recurrence rate.There are no significant adverse reactions,so it is worthy of clinical application.