尿HBsAg检测在2031名小学生健康年检中的意义

Clinical value of urine HBsAg detection in the annual health examination of 2031 children

目的探讨尿乙肝病毒表面抗原(HBsAg)检测的应用价值。方法选取2016年9月1日至10日上海市两所小学一至五年级全体小学生共2 031人为研究对象,其中市区小学980人和郊区小学1 051人。所有小学生均于开学第二周的周一留晨尿,应用ELISA方法检测尿中HBsAg,并对尿检阳性者予抽血复查乙肝相关指标。结果市区小学中980人,1人尿中HBsAg呈弱阳性,经专科医院复检后为阴性;郊区小学中1 051人,5人尿中HBsAg呈阳性,经专科医院血液检查,其中4人为HBsAg携带者,1人为大三阳(即HBsAg、HBeAg、HBcAb均阳性),5人肝功均正常。结论尿HBsAg检测可作为普通人群中及时发现HBsAg感染者的筛选方法之一,乙肝疫苗可较好保护机体,要按程序及时接种。

ObjectiveTo investigate the application value of HBsAg detection in urine.MethodsA total of2031pupils were included as the research subjects,980of whom were from an urban elementary school and1051from suburban school.Urine sanguinis was taken on Monday morning at the second week of a term.HBsAg in urine was detected by ELISA,and those with positive HBsAg testing were detected the hepatitis B related indexes.ResultsIn the980from the urban school,one had slightly positive HBsAg,which was proved to be negative in the reexamination at a special hospital.In the1051from the suburban school,5had positive HBsAg,and after the blood testing in a special hospital,4were HBsAg carries,and one had positive HBsAg,HBeAg and HBcAb,and all the5pupils had normal liver function.ConclusionUrine HBsAg test can be a way of screening for people with HBsAg infection.Hepatitis B vaccine can protect our health,so we should receive vaccination in time as scheduled.