小儿脑性瘫痪头MRI表现与中医证型的调查研究

Investigation of head MRI and TCM syndromes in children with cerebral palsy

目的对小儿脑性瘫痪(简称脑瘫)头MRI表现与中医证型进行调查研究。方法选择2014年1月至2016年12月沈阳市儿童医院康复科收治住院的脑瘫患儿156例。中医辨证分型肝强脾弱证93例(59.62%),脾肾亏虚证22例(14.10%),痰瘀阻络证15例(9.62%),心脾两虚证26例(16.67%)。对患儿头部进行MRI检查,分析MRI表现与中医证型的关系。结果 156例脑瘫患儿头MRI表现中,脑白质软化64例(41.02%),脑外间隙增宽41例(26.28%),侧脑室病变6例(3.84%),基底节病变19例(12.18%),髓鞘形成不良16例(10.26%),脑发育畸形3例(1.92%),胼胝体病变7例(4.49%)。头MRI表现在各中医证型中,差异具有统计学意义(P<0.05),脑白质软化与脑间隙增宽在肝强脾弱证中多于其他证型(P<0.05)。结论脑瘫患儿头MRI表现与中医证型存在一定内在联系。

ObjectiveTo study the head MRI manifestations and the TCM syndrome types in children with cerebral palsy.MethodsA total of156children with cerebral palsy were selected,who were treated in Shenyang children's Hospital from Jan.2014to Dec.2016.According to TCM syndrome differentiation,there were93cases of strong liver and weak spleen type(59.62%),22cases of spleen kidney deficiency type(14.10%),15cases of phlegm and blood stasis type(9.62%),and heart spleen weakness type(16.67%).The head of these children was examined by MRI,and the relationship between MRI manifestations and TCM syndrome types was analyzed.ResultsIn the156cases of cerebral palsy,there are64cases of leucomalacia(41.02%),41cases of extra cerebral interval widening(26.28%),6cases of lateral ventricular lesion(3.84%),19cases of basal ganglia lesion(12.18%),16cases of malformation of myelin sheath(10.26%),3cases of malformation of brain development(1.92%),and7cases of corpus callosum lesion(4.49%).The manifestations of head MRI had statistical difference in various TCM syndromes(P<0.05),and there were more cases of leucomalacia and cerebral interval widening in the strong liver and weak spleen syndrome than in other syndrome types(P<0.05).ConclusionThere is an internal relationship between the MRI manifestations and TCM syndrome types in children with cerebral palsy.