氩气凝固术联合艾司奥美拉唑肠溶片治疗206例Barrett食管患者的疗效观察

Different m ethods of treatm ent of 206 cases of Barrett's esophagus observation of efficacy

目的探讨氩气凝固术(APC)联合艾司奥美拉唑肠溶片治疗Barrett食管(BE)患者的疗效。方法回顾性分析2015年1月至2016年1月,新疆维吾尔自治区人民医院消化科行胃镜检查并被诊断为BE的284例患者的临床资料,其中78例患者口服艾司奥美拉唑肠溶片(A组);206例患者行APC联合口服艾司奥美拉唑肠溶片(B组),对比2组患者治疗前后临床疗效。结果 A组BE黏膜均未见明显缩小,B组97.57%的患者BE黏膜消失。结论 APC联合艾司奥美拉唑肠溶片对治疗BE患者病变的食管黏膜是一种简单、安全、可靠的方法,在改善患者BE症状的基础上,又起到了治愈BE病变黏膜的疗效,值得临床上广泛应用。

Objective To investigate the efficacy of Argon plasma coagulation(APC)combined with esomeprazole enteric-coated tablets in the treatment of Barrett's esophagus.Methods The clinical data of284patients with endoscopy and diagnosed BE were analyzed retrospectively from January2015to January2016in Xinjiang Uygur Autonomous Region People's Hospital.Among them,78patients were treated with estradiol enteric(group A);206patients underwent APC combined with estradiol enteric-coated tablets(group B).Compared the clinical efficacy between the two groups before and after treatment.Results The BE mucosa of group A was not significantly reduced while it was disappeared in97.6%patients in group B.Conclusion APC combined with esomeprazole enteric-coated tablets is a simple,safe and reliable method for the treatment of esophageal mucosa in patients with BE lesions.It can not only improve the symptoms of BE,but also can cure the BE lesions,which is worthy of clinical application.