新生儿急性坏死性小肠结肠炎的综合治疗效果研究

Effect of Comprehensive Treatment in Neonatal Acute Necrotizing Enterocolitis

目的探讨新生儿急性坏死性小肠结肠炎患者的综合治疗方法与效果。方法将本院2008年2月~2017年2月接诊的新生儿急性坏死性小肠结肠炎患儿120例作为研究对象,按照随机数表法分组的方式分为2组,各自60例。对照组患儿采取常规内科保守疗法,研究组患儿在内科保守疗法基础上结合手术治疗,对两组患儿临床效果与不良反应进行观察记录,并对比分析。结果研究组在Ⅰ期、Ⅱ期、Ⅲ期患者中总有效率均高于对照组,总体临床总有效率研究组高达9000%,对照组则为7333%,研究组明显高于对照组(P<005);两组患者均有不良反应发生,但研究组发生率为333%,对照组则为1667%,研究组显著低于对照组(P<005)。结论新生儿急性坏死性小肠结肠炎患儿采取常规保守治疗与手术治疗实施综合治疗,不仅可以提高临床效果,而且安全性高,值得借鉴。

Objective To investigate the comprehensive treatment and effect of neonatal acute necrotizing enterocolitis Methods A total of120children with acute necrotizing enterocolitis were randomized into the study group and control group from February2008to February2017,60cases in each group The control group was treated with conservative therapy The study group received surgery combined with conservative therapy The clinical effects and adverse reactions were observed and compared between the two groups Results The total effective rate of the study group in stageⅠ,ⅡandⅢpatients was higher than that in the control group The overall clinical efficacy of the study group was significantly higher than that in the control group(9000%vs7333%,P<005)The rate of adverse reactions in the study group was lower than that in the control group(333%vs1667%,P<005)Conclusion The surgery combined with conservative therapy can improve the effect of children with acute necrotizing enterocolitis,worthy of clinical application