对比奥曲肽与垂体后叶素治疗肝硬化上消化道出血的临床效果分析

Clinical Efficacy Comparison of Octreotide and Pituitrin in liver Cirrhosis Patients with Upper Gastrointestinal Bleeding

目的探讨分别选择奥曲肽方案以及垂体后叶素方案对肝硬化上消化道出血患者加以治疗后的临床疗效。方法选择本院2015年02月~2017年03月收治的150例肝硬化上消化道出血患者作为研究对象;利用随机数表法对肝硬化上消化道出血患者实施分组;对照组:选择垂体后叶素进行治疗;观察组:选择奥曲肽进行治疗;对肝硬化上消化道出血治疗总有效率、临床治疗起效时间以及临床止血时间进行对比。结果观察组肝硬化上消化道出血治疗总有效率(9467%)高于对照组肝硬化上消化道出血患者(7200%)极为明显(P<005);观察组临床治疗起效时间以及临床止血时间少于对照组极为明显(P<005)。结论选择奥曲肽方案对肝硬化上消化道出血患者实施保守治疗,同垂体后叶素方案比较,其可以将患者的临床治疗起效时间以及临床止血时间有效缩短,最终使得肝硬化上消化道出血患者治疗效果得以有效优化。

Objective To investigate and compare the clinical efficacy of octreotide and pituitrin in liver cirrhosis patients with upper gastrointestinal bleeding Methods A total of150liver cirrhosis patients with upper gastrointestinal bleeding were admitted to our hospital from February2015to March2017were enrolled into this study The patients were divided into two groups including control group and observation group according to the random number table method Patients in the control group received pituitrin treatment;Patients in the observation group received octreotide treatment,and the total effective rate,the acting time of clinical treatment and the time of clinical hemostasis for liver cirrhosis patients with upper gastrointestinal bleeding were compared Results The total effective rate(9467%)in the observation group was significantly higher than that in the control group(7200%),and the difference was statistically different(P<005)The clinical treatment acting time and clinical hemostatic time was less than that of the control group,and the difference was statistically different(P<005).Conclusion Compared with pituitrin program,the conservative therapy of octreotide solution for liver cirrhosis patients with upper gastrointestinal bleeding can effectively shorten the acting time of clinical treatment and the clinical hemostatic time,and ultimately optimize the therapeutic effect in liver cirrhosis patients with upper gastrointestinal bleeding