M22优化脉冲光对睑板腺功能障碍所致干眼的疗效

Effect of M22 Optimal Pulsed Technology in the treatment of dry eye caused by meibomian gland dysfunction

目的:研究M22优化脉冲光技术治疗睑板腺功能障碍(meibomian gland dysfunction,MGD)所致干眼的疗效,并用keratograph 5M干眼分析仪分析评估患者治疗前后病情变化。方法:收集汕头博德眼科医院门诊患者46例,年龄31~85(55.39±14.02)岁,行M22优化脉冲光治疗1个疗程(每月1次,共3次),治疗前后均采用kerato g rap h 5 M干眼分析仪分析评估患者泪河高度情况、泪膜破裂时间(break-up time,BUT)、脂质层、睑板腺情况的变化,采用t检验分析对比治疗前后变化情况。结果:患者治疗后泪河高度较强脉冲光治疗前明显增高,由(0.20±0.11)mm增加到(0.35±0.11)mm,BU T时间延长,由(4.98±2.13)s延长到(10.12±1.86)s,脂质层异常情况好转,有效率达93.48%,睑板腺阻塞情况减轻,有效率达84.78%以上,治疗后与治疗前差异有统计学意义(P<0.01)。结论:M22优化脉冲光技术在治疗MGD导致的干眼有较好的效果,没有出现并发症,是较安全有效地治疗方法,且keratograph 5M干眼分析仪可以较全面的对该病进行评估。

Objective:To study the efficacy of M22Optimal Pulsed Technology in the treatment of dry eye caused by meibomian gland dysfunction and to evaluate the changes of patients after treatment with keratograph5M dry eye analyzer.Methods:Forty-six patients collected from Shantou Balder Eye Hospital receiving M22Optimal Pulsed Technology treatment for three times,once a month,then using keratograph5M dry eye analyzer to assess the height of tears river,break-up time(BUT),lipid layer,and meibomian gland.The results before and after laser treatment were compared using t-test in this study.Results:After treatment,there was significant effect than those of before treatment,the BUT time was prolonged from(0.20±0.11)mm to(0.35±0.11)mm,the abnormalities of the lipid layer were alleviated,the cure rate exceeded93.48%,and the obstruction of the meibomian gland was reduced,the cure rate was higher than84.78%.The difference before and after corresponding treatment was statistically significant(P<0.01).Conclusion:M22Optimal Pulsed Technology has a good effect in the treatment of MGD-induced dry eye without complications.So M22Optimal Pulsed Technology is a safe and effective treatment method.And keratograph5M dry eye analyzer can deliver comprehensive assessment of dry eye.