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无菌小鼠在肠道菌与机体免疫互作机制研究中的应用 被引量：2

A review on immune regulation by intestinal microbiota
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摘要 肠道菌在机体健康中发挥重要作用,而其中肠道菌发挥作用的具体机制是什么?无菌小鼠作为一种动物模型,在研究肠道菌作用机制的研究中必不可缺。本综述以无菌小鼠模型为基础,探讨肠道菌对机体系统发育、维持中的作用,并重点讨论一些特有的肠道菌在免疫调控中的具体作用。 In a“superorganism”of human being,commensal bacteria play vital roles in regulating many aspects of host physiology.Germ free mice have been proven to be a valuable tool to unravel the underlying mechanisms how microbes interact with the host.This review discusses the recent research progress on microbiota and immune regulation.
作者 张征 刘志华 ZHANG Zheng;LIU Zhi-hua(Department of Gastroenterology, the Affiliated Yixing Hospital of Jiangsu University, Yixing214200, China;CAS Key Laboratory of Infection and Immunity, Institute of Biophysics, Chinese Academy of Sciences, Beijing100101)
机构地区 江苏省宜兴市人民医院消化内科 中国科学院生物物理研究所
出处 《中国实验动物学报》 CSCD 北大核心 2017年第6期663-666,共4页 Acta Laboratorium Animalis Scientia Sinica
关键词 无菌小鼠 肠道菌群 免疫 Germ free mice Microbiota Immunity
分类号 Q95.33 [生物学—动物学]
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共引文献10

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二级引证文献3

中国实验动物学报
2017年 第6期

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