药灸联合穴位自血疗法治疗变应性鼻炎的临床研究

Clinical Study on Allergic Rhinitis Treated by Medicinal Moxibustion Combined with Acupoints Autohemotherapy

目的:探讨药灸联合穴位自血治疗变应性鼻炎的临床效果。方法:164例变应性鼻炎患者采用随机数字表法分为两组,每组均为82例,对照组常规治疗,研究组药灸联合穴位自血治疗,观察不同方法治疗后在疗效、生活质量、中医临床症候积分、血清IgE、CD4^+、CD3^+、IL-12IFN-γ含量指标变化情况。结果:两组治疗末喷嚏、流涕、鼻塞、鼻痒、鼻黏膜肿胀积分均显著低于治疗前(P<0.05),治疗末研究组以上积分显著优于对照组(P<0.05);两组治疗末在生活质量指标日常活动、睡眠、非鼻眼症状、实际问题、鼻部症状、眼部症状、情感较治疗前均显著下降(P<0.05),治疗末研究组以上指标显著优于对照组(P<0.05);疗效上,对照组显效率28.05%、总有效率74.39%,研究组显效率42.68%、总有效率87.8%,研究组显著优于对照组(P<0.05);对照组治疗前、治疗末IgE、CD4^+、CD3^+、IL-12、IL-12含量无显著差异(P>0.05),研究组治疗末IgE较治疗前显著下降,余均显著升高(P<0.05),治疗末研究组以上含量水平显著优于对照组(P<0.05)。结论:药灸联合穴位自血治疗变应性鼻炎能改善生活质量,缓解临床症状,促进免疫力修复,提高疗效。

Objective:To explore the clinical effect of medicinal moxibustion combined with acupoints autohemotherapy in the treatment of allergic rhinitis.Methods:164patients with allergic rhinitis were randomly divided into the control group(n=82)and the observation group(n=82);the control group was given conventional treatment,and the observation group was given medicinal moxibustion combined with acupoints autohemotherapy.After treatment,the curative effect,patients life quality,clinical symptom score were analyzed,and the serum levels of IgE,CD4+,CD3+,IL-12,and IFN-γwere evaluated in the two groups.Results:The symptom scores of sneezing,running nose,nasal obstruction,nasal itching,and nasal swelling became significantly lower after the treatment than those before the treatment in the both groups,in which the observation group was superior to the control group(P<0.05).The life quality,such as daily activity,sleep quality,non-nasal symptoms,nasal and optic symptoms,and mental state,was significantly improved after the treatment in the two groups,in which the observation group was superior to the control group(P<0.05).The marked effective rate was28.05%and the total efficacy was74.39%in the control group;whereas it was4268%and87.8%correspondingly in the observation group,which was superior to the control group(P<005).There was no significant difference in terms of the levels of IgE,CD4+,CD3+,IL-12,and IFN-γbefore and after the treatment in the control group(P>0.05);the level of IgE in the observation group was significantly decreased,and the levels of CD4+,CD3+,IL-12,and IFN-γwere greatly increased after the treatment(P<0.05);the observation group was superior to the control group(P<0.05).Conclusion:The therapy of medicinal moxibustion combined with acupoints autohemotherapy has obvious effect on allergic rhinitis,it can improve patient's life quality,relieve clinical symptoms,promote immune repair and improve the curative effect.