内镜黏膜下剥离术后食管狭窄的预防研究进展

Advances in the prevention of postoperative stricture after endoscopic submucosal dissection

随着消化内镜技术的发展,内镜黏膜下剥离术(ESD)已经成为治疗食管早癌主要的手段。目前,ESD可将食管大面积早癌甚至食管环周的病变进行完整的剥离,在进行治疗的同时,通过提供更全面准确的病理诊断来指导下一步的治疗及评估患者的预后。但是,食管早癌ESD术后的并发症主要为食管狭窄。目前,对于食管狭窄的预防,仍是世界性的难题。本文对近些年来食管早癌ESD术后狭窄预防方法的相关研究进行了综述,为临床选择合适的预防食管狭窄的方法提供参考依据。

With the development of endoscopic technology,endoscopic submucosal dissection(ESD)has become the main means for the treatment of digestive early esophageal cancer.At present,ESD can be used to dissect large and even entire circumferential early esophageal cancer,not only for the treatment but providing comprehensive and precise pathological diagnosis to guide subsequent therapy and to assess the prognosis.However,the main complication after ESD is esophageal stricture.At present,the prevention of esophageal stricture is still a worldwide problem.In this paper,studies on the prevention of esophageal stricture after ESD in recent years are reviewed,which may provide a reference for the clinical selection of appropriate methods for the prevention of esophageal stricture.