医院多重耐药菌感染目标性监测与危险因素分析

Targeted monitoring of multi-drug resistant bacteria infection and analysis of its risk factors

目的:分析多重耐药菌(MDROs)医院感染的危险因素,为临床控制MDROs感染,制定预防与控制措施提供依据。方法:通过目标性监测,了解MDROs的科室分布、病原菌种类、标本来源情况,分析MDROs医院感染危险因素。结果:该院2014年共检出MDROs感染病原菌267株,检出最多的科室是重症监护室,占18.73%;检出最多的菌种是大肠埃希菌,占58.05%;标本主要来源于尿和痰,分别占36.33%和31.09%;多因素分析显示,住院时间长、患高血压、使用呼吸机、留置导尿管和手术均是MDROs医院感染的独立危险因素(P<0.05~P<0.01)。结论:MDROs医院感染与住院时间、患高血压、使用呼吸机、留置导尿管和手术等多种因素有关,应针对多种危险因素采取控制措施,从而提高医院感染的控制效率和诊疗质量,促进病人预后。

bjective:To analyze the risk factors of multi-drug resistant organisms(MDROs)infection for providing the basis in controlling infection and formulating prevention and control measures.Methods:The distribution,pathogenic species and specimens origin of MDROs were investigated by targeted monitoring,and the risk factors of MDROs infections were analyzed.Results:Two hundred and sixty-seven strains of MDROs were detected in2014.The MDROs were mostly isolated from Intensive care unit(18.73%),and the largest amount of MDROs was ESBLs-producing E.coli(58.05%).The main specimens origin were urine(36.33%)and phlegm(31.09%).The multivariate analysis showed that the long hospital stay,hypertension,using respirator,indwelling catheter and operation were the independent risk factors of MDROs infection(P<0.05to P<0.01).Conclusions:The MDROs infection is related to the hospital stay time,hypertension,using respirator,indwelling catheter and operation.The relevant control measures should be implemented according to the risk factors in order to improve the efficiency of controlling hospital infection and quality of diagnosis,and promote prognosis of patients.