摘要
纳米药物是纳米技术在医药领域的应用。与常规药物相比,纳米药物在实现靶向给药、缓控释给药、提高药物溶解度及生物利用度、降低毒副作用等方面具有良好的发展前景。本研究通过统计数据分析纳米药物从理论研究探索到商业上市各阶段的发展状况,包括纳米药物数量、重要研发国家与公司、主要适应症与作用机制的分布、具有较高商业价值的热点药物等,分析纳米药物的总体发展趋势,揭示其竞争态势和主要发展方向。
Nanodrug research is an application of nanotechnology in medical area.Compared with conventional drugs,nanodrug have promising development prospects in many aspects,including but not limited in targeted drug delivery,controlled release of drugs,improvement of drug solubility and bioavailability,and reduction of toxic effects.Through the statistical data of the nanodrug development in different stages,from theory exploration to the commercialization,this study analyze the status of nanodrug quantity,important R&D countries and companies,distribution of the main indications and mechanism,and hot drugs with high commercial value,and further discuss the overall development trends of nanodrug,reveal the global competition situation and main development directions.
作者
邢颖
吴树仙
李超
冷伏海
赵宇亮
Xing Ying;Wu Shuxian;Li Chao;Leng Fuhai;Zhao Yuliang(Institutes of Science and Development, CAS, Beijing 100190, China;National Center for Nanoscience and Technology, Beijing 100190, China)
关键词
纳米药物
纳米技术
靶向治疗
药学
nanodrug
nano-technology
targeted therapy
pharmacy