睡眠呼吸暂停低通气综合征体型特征与呼吸紊乱的关系探讨

Investigation of relationship between bodily form feature and respiratory disturbances in patients with obstructive sleep apnea/hypopnea syndrome

目的:探讨阻塞型睡眠呼吸暂停低通气综合征(OSAHS)患者体型特征与呼吸紊乱的关系。方法:经多导睡眠仪监测确诊为OSAHS患者100例,研究其体重指数(BMI)、腰围(WC)、颈围(NC)等体型特征与呼吸紊乱指标的相关性;比较BMI<25 kg/m^2(正常)、25≤BMI<30 kg/m^2(超重)和BMI≥30 kg/m^2(肥胖)三组患者的呼吸紊乱指标。结果:OSAHS患者的BMI、颈围(NC)、腰围(WC)与其呼吸紊乱指标均显著相关。不同BMI组患者,其睡眠呼吸紊乱指数、呼吸紊乱最长时间、夜间平均氧饱和度、最低血氧饱和度差异均有统计学意义(P<0.05),以BMI≥30 kg/m^2(肥胖)组的患者呼吸紊乱最为显著。结论:不同BMI的OSAHS患者其呼吸紊乱指数显著不同,体型越肥胖、腰围、颈围越大的OSAHS患者较正常体型者呼吸紊乱更为严重。

Objective To explore the relationship between bodily form feature and respiratory disturbances in patients with obstructive sleep apnea/hypopnea syndrome(OSAHS).Method One hundren patients with OSAHS confirmed by plysomnogram(PSG)were enrolled.To study the correlation between BMI,waist circumference(WC)and neck circumference(NC)of respiratory parameters.The bodily form feature and respiratory parameters were recorded and compared among those with different BMI,ie,BMI<25kg/m2,25≤BMI<30kg/m2and BMI≥30kg/m2.Results There was a significant correlation between BMI,waist circumference(WC),neck circumference(NC)and respiratory parameters.The BMI,waist circumference(WC),neck circumference(NC),apnea hypopnea,the longest time of breathing disorder and arterial oxygen saturation in sleeping time were significangtly different among OSAHS patients with different BMI(P<0.05).The disturbances of respiratory parameters were most significant in those of BMI≥30kg/m2with larger waist circumference and neck circumference.Conclusion The disturbances of respiratory parameters have a significant difference in different BMI with OSAHS.The obesity people with larger waist circumference and neck circumference are more easily get OSAHS than the normal people.