梅尼埃病患者术后抑郁状态及其与眩晕、生活质量改善的关系

Postoperative Depression of Patients with Meniere Disease and the Relationships to Vertigo and the Improvement of Quality of Life

目的探讨梅尼埃病患者术后抑郁症状及其与眩晕、生活质量改善间的关系。方法对2013年至2015年间住院并行内淋巴囊减压术的46例梅尼埃病患者的临床资料进行回顾性分析,评估抑郁自评量表、梅尼埃病治疗效果问卷结果,随访手术前后眩晕发作次数及程度;另选取95例性别、年龄、术后病程相匹配,因耳鼻喉其它疾病接受手术的患者作为对照组,填写抑郁自评量表;比较分析抑郁、眩晕、生活质量间关系。结果 43例完成抑郁自评量表的梅尼埃病患者中术后69.77%(30/43)无抑郁,13.95%(6/43)轻度抑郁,16.28%(7/43)中度抑郁,无重度抑郁者,而对照组95例均无抑郁症状。梅尼埃病患者术后眩晕与抑郁(Spearman相关系数为0.241,P>0.05)、生活质量与抑郁(Spearman相关系数为-0.205,P>0.05)均无线性相关关系。术后眩晕控制程度不同的患者之间抑郁自评量表评分没有明显统计学差异(Chi-Square统计量为1.895,P>0.05)。结论约30%梅尼埃病患者术后存在不同程度抑郁症状,且与术后眩晕控制情况、术后生活质量改善情况关系不大。

Objective To investigate the depression of patients with Meniere disease after surgery,and the relationships to vertigo and the improvement of the quality of life.Methods A total of46patients with Meniere disease and95patients with other diseases of otorhinolaryngology(as control)were enrolled in this retrospective study.They underwent operations between2013and2015.They finished self-rating depression scales,Meniere disease outcomes questionaire by snail mail.They were asked about the frequencies of vertigo before and after surgery.The gender,age and postoperative course in the control group were matched to those of in the Meniere group.The relationships among vertigo,the improvement of the quality of life and postoperative depression were compared.Results In the Meniere group,69.77%of patients did not have depression,while13.95%were with mild depression,16.28%with moderate,none with severe.Depression was more severe in the Meniere group than in the control group.There were no obvious linear relationships between vertigo and depression or between quality of life and depression.There was no statistical difference in depression of patients with different vertigo frequencies.Conclusion There is still a certain degree of postoperative depression in near30%of patients with Meniere disease after surgery.This may not be related to vertigo nor the quality of life.