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HMGB-1和TSGF联合检测诊断甲状腺癌的价值分析

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摘要 目的探讨HMGB-1(高迁移率蛋白1)和TSGF(肿瘤特异性生长因子)联合检测在甲状腺癌诊断中的临床价值。方法选择2015年1月至2016年6月来该院就诊的甲状腺癌患者90例为观察组研究对象,选择同时期甲状腺良性肿瘤患者85例及健康体检者70例为对照组研究对象,对所有患者均进行HMGB-1及TSGF检测,并分析各组检测结果。结果甲状腺癌患者血浆HMGB-1与TSGF水平远远高于其他两组(P<0.05),同时两项指标联合检测的灵敏度为92.22%,远远高于单独检测(P<0.05),同时伴有淋巴转移的甲状腺癌患者血浆中TSGF的水平远远高于不伴淋巴转移的甲状腺癌患者(P<0.05)。结论HMGB-1与TSGF联合检测应用于甲状腺癌患者的早期诊断中,具有十分重要的借鉴意义,能够明显提高甲状腺癌诊断的灵敏度,并且TSGF可作为判断甲状腺癌有无淋巴转移的重要指标。
作者 吴苏君
出处 《国际检验医学杂志》 CAS 2017年第A02期157-159,共3页 International Journal of Laboratory Medicine
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