产前超声对妊娠期糖尿病胎儿肺发育的研究

Study on Prenatal Ultrasound on Fetal Lung Development in Gestational Diabetes Mellitus

目的探讨应用产前超声技术检测胎儿肺参数在妊娠期糖尿病孕妇的胎儿肺发育评估中的意义。方法选取2016年10月—2017年7月在青岛大学附属医院收治的妊娠期糖尿病患者38例作为研究对象。其中,血糖控制不良者入A组(8例),血糖控制良好者入B组(30例),并选择同期30例身体健康的孕妇作为对照组(C组)。应用二维超声技术对各组孕妇分别在孕24~25+6周、28~29+6周及34~35+6周时测量胎儿肺的相关参数,其中包括左右肺纵径、总肺面积及总肺体积。对比分析三组胎儿肺的相关参数以探讨其与妊娠期糖尿病的相关性。结果 A组胎儿肺的各参数值大于C组,但B组胎儿肺的各参数值与C组比较,差异无统计学意义(P>0.05)。结论利用产前超声技术来评估妊娠期糖尿病孕妇的胎儿肺发育具有较高的临床价值。

Objective To investigate the significance of the application of prenatal ultrasound technology to the fetal lung development evaluation in gestational diabetes mellitus.Methods38cases of gestational diabetes treated in the Affiliated Hospital of Qingdao University from October2016to July2017were selected as the research subjects.Among them,the patients with poor control of blood glucose were enrolled in group A(8cases),and those with good blood glucose control were enrolled in groupB(30cases).30healthy pregnant women were selected as the control group(group C)at the same time.Two dimensional ultrasound was used to measure fetal lung parameters in pregnant women from24to25+6weeks,28to29+6weeks and34to35+6weeks,including the longitudinal diameterof the left and right lungs,the total lung area and the total lung volume.The correlation between three groups of fetal lung parameters was compared and analyzed in order to explore the correlation with gestational diabetes.Results The parameters of fetal lung in group A were greater than that in group C,but there was no significant difference in the parameters of fetal lung in group B compared with that of group C(P>0.05).Conclusion The application of prenatal ultrasound technique to evaluate fetal lung examination is of higher clinical value for the fetal lung development in pregnancy.