硫酸镁与山莨菪碱治疗早发型重度子痫前期临床效果对比

Comparison of the Clinical Effect of Magnesium Sulfate and Anisodamine in the Treatment of Early Onset Severe Preeclampsia

目的对硫酸镁与山莨菪碱治疗早发型重度子痫前期临床效果进行比较。方法选取我院2015年2月—2017年2月收治的早发型重度子痫前期患者110例作为研究对象。根据治疗方法不同,将其分为A、B两组,每组各55例。A组患者采取硫酸镁治疗,B组患者采取山莨菪碱治疗,对比两组患者治疗效果。结果治疗后,两组患者收缩压、舒张压、蛋白尿水平均有所下降,组间比较,差异不具有统计学意义(P>0.05);A组患者水肿消退23例(41.82%),B组患者水肿消退34例(61.82%),B组患者水肿改善情况优于A组,差异具有统计学意义(P<0.05)。结论硫酸镁与山莨菪碱治疗早发型重度子痫前期均可获得较好的效果,但山莨菪碱在改善患者水肿方面具有一定优势。

Objective Tocomparethe clinical effects of Magnesium Sulfate and anisodamine in the treatment of early onset severe preeclampsia were compared.Methods110cases of early onset severe preeclampsia were selected from February2015to February2017in our hospital.According to the different treatment methods,it was divided into two groups of A and B,55cases in each group.The patients in group A were treated with magnesium sulfate.The patients in group B were treated with anisodamine.The treatment effect was compared between the two groups.Results After treatment,the systolic pressure,diastolic pressure and proteinuria water in the two groups were decreased,and the difference was not statistically significant(P>0.05).In group A,edema disappeared in23cases(41.82%).In group B,edema disappeared in34cases(61.82%),and edema in group B was better than that in group A(P<0.05).Conclusion Magnesium sulfate and anisodamine are effective in the treatment of early-onset severe preeclampsia,but anisodamine has some advantages in improving the edema of patients.