下肢难治性溃疡的新技术治疗

A New Treatment of Lower Extremity Chronic Refractory Ulcers

目的:探讨治疗下肢难治性溃疡的新治疗手段。方法:选取2016年1月至2017年10月随机收入院的下肢难治性溃疡患者32例,采用水动力系统清创,负压创面治疗技术行创面床准备,结合富血小板血浆辅助游离植皮术修复创面。结果:30例植皮区完全成活,2例大部分成活,经二期清创植皮后,痊愈;治愈率为93.7%,随访6~12个月,无1例复发。结论:水刀清创联合负压吸引技术,结合PRP辅助游离植皮术修复溃疡创面,既可提高修复成功率又可有效减少供区损伤,不失为一种治疗难治性溃疡创面的新方法。

Objective To investigate the new therapy to treat lower extremity chronic refractory ulcers.Methods From January2016to October2017,32patients with lower extremity chronic refractory ulcers were treated.Hydrosurgery for debridement,NPWT for wound preparation and PRP assisted skin graft were combined to treat chronic wound.Results The graft of30patients were healed completely while2patients has a slight graft loss because of severe infection,and completely cured after second debridement and skin graft.The clinical cure rate is about93.7%.All patients were followed up for6to12months with no recurrence.Conclusion The combination of hydrosurgery,PRP,NPWT and skin graft has an obvious curative effect for treatment of lower extremity chronic refractory ulcers.This new therapy may serve as an innovative regimen for its ability to promote wound healing,reduce damage to donor sites and shorten course of therapy.