二维斑点追踪技术对绝经期妇女左心室收缩功能的评价

Evaluation of the Left Ventricular Systolic Fuction in Postmenopausal Women by Two-Dimensional Speckle Tracking Echocardiography

目的探讨二维斑点追踪技术评估绝经期妇女左心室收缩功能的改变。方法选择绝经期妇女41例以及年龄匹配的非绝经期妇女46例纳入研究。常规测量左心室舒张末容积(Left Ventricular Enddiastolic Volume,LVEDV)、左心室收缩末容积(Left Ventricular End-Systolic Volume,LVESV)、左心室射血分数(Left Ventricular Ejection Fraction,LVEF)以及室间隔和左心室后壁厚度,行二维超声心动图检查,获取左心室整体纵向收缩峰值应变(Global Longitudinal Peak Systolic Strain,GLS)、整体圆周收缩峰值应变(Global Circumferential Peak Systolic Strain,GCS)以及整体径向收缩峰值应变(Global Radial Peak Systolic Strain,GRS)。结果两组LVEF、LVEDV、LVESV以及室间隔和左心室后壁厚度无统计学差异(P>0.05);与绝经前组比较,绝经后组左心室GLS显著减低(P<0.05),两组GRS以及GCS无统计学差异(P>0.05)。结论绝经期妇女左心室二维纵向应变显著减低,二维斑点追踪技术是评估绝经期妇女心脏功能以及轻微左心室功能受损的可行方法。

Objective The aim of this study was to assess the change left ventricular function in post-menopause women by using two-dimensional speckle tracking echocardiography.Methods A total of 41 post-menopause women were included,and the control group included 46 age-matched premenopause women.Conventional echocardiography and two-dimensional speckle-tracking echocardiography(2D-STE)were performed and the left ventricular enddiastolic volume(LVEDV),left ventricular end-systolic volume(LVESV),left ventricular ejection fraction(LVEF),left ventricular global longitudinal peak systolic strain(GLS),global circumferential peak systolic strain(GCS),and global radial peak systolic strain(GRS)were measured.Results LVEDV,LVESV,LVEF,GRS and GCS were similar between post-menopause women and pre-menopause women(P>0.05).GLS was significantly reduced in post-menopause women compared to pre-menopause women(P<0.05).Conclusion In menopause women,2D-STE reveals lower longitudinal strain values than non-menopause women.2D-STE is a feasible method to assess cardiac function and appears suitable to detect subtle left ventricular dysfunction.