微光刀立体定向放射治疗系统剂量学测试

Dosimetric Test for Stereotactic Radiotherapy System of D2SRS

目的对微光刀立体定向放射治疗系统(Dual Camera 2 mm Stereotactic Radiosurgerg,D2SRS)临床剂量学可靠性进行测试、研究。方法随机选取20例已接受放射治疗的病例,其中包括7例颅内肿瘤、6例肺部肿瘤和7例肝癌病例,将20例病例的CT图像和RT Structures通过DICOM网络分别传输至雷泰Ti GRT计划系统和Eclipse11.0计划系统,进行放射治疗计划设计,统计两组靶区及危及器官的剂量学参数并进行统计学分析,将两组调强计划分别进行绝对剂量和二维面剂量验证,并比较两组计划的绝对剂量和二维平面剂量验证结果。结果两组计划均能满足临床剂量要求,靶区剂量学参数D_(98)、D_(50)、D_(02)、CI以及HI均无统计学差异(P>0.05);危及器官受照剂量如全脑、心脏、食管、肝脏和肾脏的D_(mean)、脑干和脊髓D_(max)、双肺V_(20)等剂量学参数均无统计学差异(P>0.05);Eclipse与Ti GRT两组计划的验证结果显示,点剂量误差统计结果为(0.70±1.44,0.57±1.86,t=0.268,P=0.796);二维面剂量Gamma分析统计结果为(96.8%±0.9%,97.3%±1.2%,t=2.031,P=0.056)。结论D2SRS在剂量精确性上达到同类型进口设备相似水平。

Objective To carry out a clinical dosimety reliability test and research for the radiotherapy system of dual camera 2 mm stereotactic radiosurgerg(D2SRS).Methods We randomly selected 20 cases which received radiotherapy,including 7 cases of intracranial tumors,6 cases of lung cancer and 7 cases of liver cancer.Then CT images and RT structures of 20 cases were separately transported to TiGRT TPS and Eclipse11.0 system by DICOM network,and radiation treatment planning design were performed.The dosimetric parameters of target and organ at risk(OAR)of two groups were acquireed and statistical analysis was carried out.Absolute dose and two-dimensional dose of two intensity-modulated plan groups was eparately verified,and their dose verification results were compared.Results Two groups were able to meet the clinical dose requirements,and the dose parameters of target such as D98,D50,D02,CI and HI were no significantly statistical difference(P=0.563,0.175,0.372,0.265,0.245).There were no significant differences in Dmean of whole brain,heart,esophagus,liver and kidneys,Dmax of brain stem and spinal cord,V20 of both lungs(P=0.224,0.890,0.530,0.750,0.082,0.790,0.180,0.795).The dose verification results of Eclipse and TiGRT indicated that the point dose error was(0.70±1.44,0.57±1.86,t=0.268,P=0.796),and the tow-dimensional dose Gamma analysis was(96.8%±0.9%,97.3%±1.2%,t=2.031,P=0.056).Conclusion The radiotherapy system of D2SRS is upto the similar level of the imported equipment in the dose precision,and this independent industry can be promoted to the clinical application in clinical perspective.