探讨硝苯地平、酚妥拉明和硫酸镁三联用药治疗妊娠期高血压疾病的临床疗效及对妊娠结局的影响

The clinical efficacy of nifedipine,phentolamine and Magnesium Sulfate in the treatment of pregnancy induced hypertension and its effect on pregnancy outcome

目的:明确硫酸镁、酚妥拉明以及硝苯地平三联用药方法治疗妊娠期高血压疾病的实际临床效果以及对妊娠结局的影响。方法:选取本院收治的96例妊娠期高血压疾病患者作为研究对象,将其随机分成单一组和三联组,每组48例。单一组患者应用硫酸镁进行治疗,联合组患者在单一组患者治疗基础之上加用硝苯地平以及酚妥拉明开展治疗。对两组患者临床治疗效果以及妊娠结局进行对比。结果:三联组患者临床治疗效果显著优于单一组患者,P<0.05;三联组患者妊娠结局显著优于单一组患者,P<0.05。结论:三联用药治疗妊娠期高血压疾病具有显著的效果,具有临床推广价值。

Objective:To determine the Magnesium Sulfate actual clinical effect of phentolamine and nifedipine combined treat-ment methods for the treatment of pregnancy induced hypertension and its effect on pregnancy outcome.Methods:96cases of patients with hypertensive disorders in pregnancy in our hospital as the research object,randomly divided into single group and triple therapy group,48cases in each group.The single Magnesium Sulfate group of patients with treatment,the patients in a single group of patients based on the use of nifedipine and phentolamine in treatment The comparison of two groups of patients with clinical curative effect and pregnancy outcomes were analyzed.Results:the clinical effect of the treatment group were sig-nificantly better than the single triple group P<C0.05and triple group had significantly better pregnancy outcomes than single group patients.P<C0.05.Conclusion:triple therapy has significant effect in the treatment of hypertensive disorder complica-ting pregnancy,and has the value of clinical promotion.