糖尿病干眼的相关研究进展

Research progress on dry eye in diabetes mellitus

随着人们生活习惯及环境的改变,干眼已经成为眼科门诊最常见的疾病之一。糖尿病可引起眼部多种并发症,如白内障及糖尿病视网膜病变等。近年研究发现高血糖及糖尿病人群干眼发病率较正常人群高,糖尿病亦是干眼发病的重要危险因素。然而目前糖尿病干眼的相关机制及临床特征尚不完全清楚,多数研究只针对单纯干眼患者,本文将近年来糖尿病干眼患病率、病因、发病机制、临床表现及预防治疗的相关研究做一综述。

With the alterations of people’s living habits and environment,dry eye has become one of the most common diseases in ophthalmic clinic.Diabetes mellitus can cause a variety of ophthalmic complications,such as cataract and diabetic retinopathy.Recently,some studies show that there is higher incidence of dry eye in hyperglycemia and diabetic patients,and diabetes is one of the important risk factors for dry eye.However,the relevant mechanisms and clinical features of diabetic dry eye are not fully understood,and most studies only focus on patients with dry eyes.In this review,we discuss the prevalence,etiology,pathogenesis,clinical characteristics,prevention and treatment for diabetes-related dry eye.