丹参多酚酸盐治疗冠心病的临床疗效及安全性分析

Safety and clinical efficacy of salvianolate on coronary heart disease

目的:观察与探究丹参多酚酸盐治疗冠心病的临床疗效及安全性。方法:选取2016年3月-2017年3月于本院就诊及治疗的55例冠心病患者作为研究对象,按照随机数字表法分为两组,对照组27例患者给予丹参注射液治疗,观察组28例患者给予丹参多酚酸盐治疗,对比并分析两组患者的效果。结果:观察组患者的治疗总有效率(92.86%)与对照组患者(70.37%)相对比,差异比较明显(P<0.05),观察组患者的恶心、腹胀等不良反应总发生率(3.57%)与对照组患者(7.41%)相对比,差异不明显(P>0.05)。结论:对冠心病患者应用丹参多酚酸盐治疗的效果较好,未增加患者的不良反应,具有一定的安全性。

Objective:To observe and explore safety and clinical efficacy of salvianolate on coronary heart disease.Methods:55cases in our hospital from March2016to March2017were randomly divided into two groups according to the random digital table.27patients in the control group were given the Danshen injection;28patients in the observation group were treated with salvianolate.Results:The total efficiency(92.86%)in the observation group was significantly higher than70.37%in the control group;the difference between the groups was significant(P<0.05).The total incidence of adverse reactions such as nausea and bloating in the observation group(3.57%)showed no difference compared with7.41%in the control group(P>0.05).Conclusion:Salvianolate showed a better effect,did not increase the adverse reactions of patients,with a certain degree of safety.