泮托拉唑与奥美拉唑治疗老年消化性溃疡疗效对比研究

Comparative study of pantoprazole and omeprazole in the treatment of senile peptic ulcer

目的:对比泮托拉唑与奥美拉唑治疗老年消化性溃疡的效果。方法:收治老年消化性溃疡患者82例,随机平分两组。对照组使用奥美拉唑治疗,研究组使用半托拉唑治疗,对比两组治疗效果。结果:研究组临床总有效率95.1%,高于对照组的80.5%,差异有统计学意义(P<0.05)。两组均未发生不良反应。结论:在老年消化性溃疡临床治疗中,泮托拉唑能够缓解症状,不良反应少,临床用药不需要调整剂量,可作为首选治疗药物。

Objective:To compare the effect of pantoprazole and omeprazole in the treatment of peptic ulcers in the elderly.Methods:82 elderly patients with peptic ulcers were selected.They were randomly divided into the two groups on average.The control group was treated with omeprazole,and the study group was treated with pantoprazole.We compared the therapeutic effect of patients in the two groups.Results:The clinical efficacy of the study group 95.1%,higher than 80.5%of the control group,and the difference was statistically significant(P<0.05).No adverse reactions occurred in both groups.Conclusion:Pantoprazole can relieve symptoms and reduce adverse reactions in the treatment of peptic ulcer in elderly patients.It is not necessary to adjust dosage for clinical medication,so it can be used as the first choice for treatment.