雷贝拉唑联合克拉霉素、阿莫西林治疗胃溃疡的效果观察

Observation on the effect of rabeprazole combined with clarithromycin,amoxicillin in the treatment of gastric ulcer

目的:观察雷贝拉唑联合克拉霉素、阿莫西林治疗胃溃疡的效果。方法:收治胃溃疡患者96例,随机平分两组。对照组使用奥美拉唑、克拉霉素、阿莫西林治疗,研究组使用雷贝拉唑联合克拉霉素、阿莫西林治疗,对比两种方式的治疗效果。结果:研究组治疗后腹痛总缓解率93.7%,高于对照组的79.2%;治疗总有效率95.8%,高于对照组的81.2%,与对照组比较,差异有统计学意义(P<0.05)。两组均未发生明显不良反应。结论:雷贝拉唑联合克拉霉素、阿莫西林治疗的效果显著,能够快速起效,不良反应少。

Objective:To observe the effect of rabeprazole combined with clarithromycin,amoxicillin in the treatment of gastric ulcer.Methods:96 patients with gastric ulcer were selected.They were randomly divided into the two groups on average.The control group was treated with omeprazole,clarithromycin and amoxicillin.The research group used rabeprazole combined with clarithromycin,amoxicillin treatment.We compared the therapeutic effects of two ways.Results:The total remission rate of abdominal pain after treatment in the study group was 93.7%,higher than that of the control group(79.2%);the total effective rate was 95.8%higher than that of the control group(81.2%);compared with the control group,the difference was statistically significant(P<0.05).There was no obvious adverse reaction in all two groups.Conclusion:The effect of rabeprazole combined with clarithromycin and amoxicillin is significant,and it can start quickly and have less adverse reactions.